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Part number: H2ax

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H2ax Component Specifications

General Information: The H2ax component is a specialized part designed for use in biological research, specifically in the field of DNA damage and repair studies. This component is known for its high sensitivity and accuracy in detecting DNA double-strand breaks.

Specifications

  • Function: Specifically targets phosphorylated histone H2AX (γH2AX) molecules to indicate sites of DNA damage, providing valuable insights into cellular responses to genotoxic stress.
  • Compatibility: Compatible with various immunofluorescence and immunohistochemistry techniques, allowing for precise visualization and quantification of DNA damage foci.
  • Sensitivity: Offers high sensitivity in detecting even low levels of DNA damage, making it a crucial tool in research related to cancer, aging, and genetic disorders.
  • Accuracy: Provides accurate and reliable results, enabling researchers to study DNA repair mechanisms and evaluate the efficacy of genotoxic treatments.

Applications

  • Research: Widely used in laboratories and research facilities to study DNA damage, repair pathways, and genomic instability in various biological systems.
  • Cancer Studies: Essential tool in cancer research to assess DNA damage response, predict treatment outcomes, and develop targeted therapies for different cancer types.
  • Drug Development: Utilized in pharmaceutical research to evaluate the genotoxic effects of potential drug candidates and assess their impact on DNA integrity.

Compliance

Industry Standards: The H2ax component complies with established protocols and guidelines in the field of molecular biology and cellular research, ensuring reproducibility and accuracy in experimental results.

Identification

The designation H2ax signifies a critical component in DNA damage analysis, highlighting its importance in studying cellular responses to genotoxic stress and advancing our understanding of DNA repair mechanisms.

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